A thermodynamic theory of microbial growth
Une théorie thermodynamique de la croissance microbienne
Desmond-Le Quéméner, E. ; Bouchez, T.
Type de document
Article de revue scientifique à comité de lecture
Affiliation de l'auteur
IRSTEA ANTONY UR HBAN FRA ; IRSTEA ANTONY UR HBAN FRA
Résumé / Abstract
Our ability to model the growth of microbes only relies on empirical laws, fundamentally restricting our understanding and predictive capacity in many environmental systems. In particular, the link between energy balances and growth dynamics is still not understood. Here we demonstrate a microbial growth equation relying on an explicit theoretical ground sustained by Boltzmann statistics, thus establishing a relationship between microbial growth rate and available energy. The validity of our equation was then questioned by analyzing the microbial isotopic fractionation phenomenon, which can be viewed as a kinetic consequence of the differences in energy contents of isotopic isomers used for growth. We illustrate how the associated theoretical predictions are actually consistent with recent experimental evidences. Our work links microbial population dynamics to the thermodynamic driving forces of the ecosystem, which opens the door to many biotechnological and ecological developments.
Isme Journal, vol. 8, num. 8, p. 1747 - 1751